Timeline: 1501-1510
1501
- Births: Anne Boleyn (August 16)
1502
- The bell ringer at the Notre Dame Cathedral in Paris, the hunchback Quasimodo (20), meets the kindly Gypsy woman Esmeralda ().
1503
- Leonardo da Vinci (51) paints the Mona Lisa.1
- Births: Michel de Nostredame (December 14)2
1504
- The Doctor (third incarnation) and Sarah Jane Smith (22/1974) arrive in Italy, and witness the origins of the "sorcerer" Maximilian.3
1505
- The last Jagaroth Scaroth has Leonardo da Vinci (53) paint six additional copies of the Mona Lisa. The Doctor (fourth incarnation) briefly appears here and intersects with Scaroth. The Doctor vandalizes the Mona Lisas.4
1506
- May 20. Christopher Columbus (55) dies.
1507
- March 29. An immortal comes into existence near Glenfinnan, Scotland.
1508
- November 15. Harriet is born on Apokolips.
1509
- April 21. Henry VIII ascends to become King of England.
1510
- September 29. Agatha Harkness is born.